MIG Workshop: Mechanistic inference from single-cell data

This workshop covers basics of parameter estimation and uncertainty by fitting stochastic gene expression models to scRNA-seq data. About the Workshop Parameter inference is essential for interpreting empirical data and validating mechanistic models. In this workshop, we will cover the basics of parameter estimation and uncertainty quantification by fitting stochastic models of gene expression to single-cell RNA sequencing data. We will implement maximum likelihood and Bayesian inference methods in Julia and explore the issue of parameter identifiability along with its practical implications for model selection. We will also discuss how to distinguish the different sources of biological and technical noise present in high-throughput single-cell data. This workshop builds on top of the fundamentals of biochemical modelling covered in October workshop of the series. Pre-requisites: some familiarity with statistics and programming would be beneficial. Lead Instructors: Lucy Ham, Augustinas Sukys & Kaan Ocal Please note that the $25 booking fee will be fully refunded upon workshop attendance. ----------------------------------------------------------------------------------------------------- Registration & Cancellation Policy To secure your spot in a workshop, we require a nominal fee, which will be fully refunded upon your attendance at the workshop. This policy helps ensure commitment and allows us to manage resources effectively. Cancellations Made in Advance: If you need to cancel your registration, you must notify us at least 72 hours before the workshop start time. In such cases, the nominal fee will be fully refunded. Refunds will happen within one week of the event. No-Show Policy: If you do not attend the workshop and have not cancelled in advance, the nominal fee will be retained and will not be refunded. Late Cancellations: Cancellations made less than 72 hours before the workshop will be treated as a no-show, and the nominal fee will not be refunded. Illness or Exceptional Circumstances: Cancellations due to illness or exceptional circumstances will be considered on a case-by-case basis, and refunds will be provided at MIG's discretion. This policy ensures fairness to all participants and helps us plan workshops efficiently. Thank you for your understanding. If you have any questions or need assistance with your registration, please contact us at [email protected]